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  1. The major difficulty in postoperative care in patients after craniotomy is to distinguish the intracranial deficits from the residual effect of general anesthesia. In present study, we used cerebral state inde...

    Authors: Ming Xu, Yan-Ni Lei and Jian-Xin Zhou

    Citation: BMC Neurology 2011 11:15

    Content type: Research article

    Published on:

  2. Stroke is a major cause of death and leading cause of disability in the United States. To maximize a stroke patient's chances of receiving thrombolytic treatment for acute ischemic stroke, it is important to i...

    Authors: Prasanthi Govindarajan, David Ghilarducci, Charles McCulloch, Jessica Pierog, Evan Bloom and Claiborne Johnston

    Citation: BMC Neurology 2011 11:14

    Content type: Study protocol

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  3. The clinical presentation in progressive supranuclear palsy (PSP), an atypical parkinsonian disorder, includes varying degrees of frontal dysexecutive symptoms. Using diffusion tensor imaging (DTI) and tractog...

    Authors: Pia Kvickström, Bengt Eriksson, Danielle van Westen, Jimmy Lätt, Christina Elfgren and Christer Nilsson

    Citation: BMC Neurology 2011 11:13

    Content type: Research article

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  4. Acute/subacute cerebral infarction (ASCI) in HIV-negative cryptococcal meningoencephalitis (CM) adults has rarely been examined by a series of MRI-based follow-up study. We studied a series of MRI follow-up st...

    Authors: Shu-Fang Chen, Cheng-Hsien Lu, Chun-Chung Lui, Chi-Ren Huang, Yao-Chung Chuang, Teng-Yeow Tan, Nai-Wen Tsai, Chiung-Chih Chang, Wan-Chen Tsai and Wen-Neng Chang

    Citation: BMC Neurology 2011 11:12

    Content type: Research article

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  6. Epilepsy is a neurological disorder, characterized by recurrent unprovoked seizures which have a high impact on the individual as well as on society as a whole. In addition to the economic burden, epilepsy imp...

    Authors: Reina JA de Kinderen, Danielle AJE Lambrechts, Debby Postulart, Alfons GH Kessels, Jos GM Hendriksen, Albert P Aldenkamp, Silvia MAA Evers and Marian HJM Majoie

    Citation: BMC Neurology 2011 11:10

    Content type: Study protocol

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  7. Schwannomatosis is a disease characterized by multiple non-vestibular schwannomas. Although biallelic NF2 mutations are found in schwannomas, no germ line event is detected in schwannomatosis patients. In contras...

    Authors: Guillaume Rousseau, Tetsuro Noguchi, Violaine Bourdon, Hagay Sobol and Sylviane Olschwang

    Citation: BMC Neurology 2011 11:9

    Content type: Research article

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  9. Neuropathic pain (NeP) is a common symptom of a group of a variety of conditions, including diabetic neuropathy, trigeminal neuralgia, or postherpetic neuralgia. Prevalence of NeP has been estimated to range b...

    Authors: Ana Navarro, María T Saldaña, Concepción Pérez, Sandra Torrades and Javier Rejas

    Citation: BMC Neurology 2011 11:7

    Content type: Research article

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  10. Stroke is a major cause of dysphagia, but little is known about when and how dysphagic patients should be fed and treated after an acute stroke. The purpose of this study is to establish the feasibility, risks...

    Authors: Hideaki Takahata, Keisuke Tsutsumi, Hiroshi Baba, Izumi Nagata and Masahiro Yonekura

    Citation: BMC Neurology 2011 11:6

    Content type: Research article

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  11. The variations of the circle of Willis (CW) are clinically important as patients with effective collateral circulations have a lower risk of transient ischemic attack and stroke than those with ineffective col...

    Authors: K Ranil D De Silva, Rukmal Silva, Dhammika Amaratunga, WSL Gunasekera and Rohan W Jayesekera

    Citation: BMC Neurology 2011 11:5

    Content type: Research article

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  12. DNA polymerase γ (POLG) is the only known mitochondrial DNA (mtDNA) polymerase. It mediates mtDNA replication and base excision repair. Mutations in the POLG gene lead to reduction of functional mtDNA (mtDNA depl...

    Authors: André Schaller, Dagmar Hahn, Christopher B Jackson, Ilse Kern, Christophe Chardot, Dominique C Belli, Sabina Gallati and Jean-Marc Nuoffer

    Citation: BMC Neurology 2011 11:4

    Content type: Research article

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  13. Epilepsy affects an estimated 50 million people and accounts for approximately 1% of days lost to ill health globally, making it one of the most common, serious neurological disorders. While there are abundant...

    Authors: Maree L Hackett, Nicholas S Glozier, Alexandra L Martiniuk, Stephen Jan and Craig S Anderson

    Citation: BMC Neurology 2011 11:3

    Content type: Study protocol

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  14. Delayed arrival at hospital is one of the major obstacles in enhancing the rate of thrombolysis therapy in patients with acute ischemic stroke. Our study aimed to investigate factors associated with prehospita...

    Authors: Young Seo Kim, Sang-Soon Park, Hee-Joon Bae, A-Hyun Cho, Yong-Jin Cho, Moon-Ku Han, Ji Hoe Heo, Kyusik Kang, Dong-Eog Kim, Hahn Young Kim, Gyeong-Moon Kim, Sun Uk Kwon, Hyung-Min Kwon, Byung-Chul Lee, Kyung Bok Lee, Seung-Hoon Lee…

    Citation: BMC Neurology 2011 11:2

    Content type: Research article

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  16. Medication-overuse headache (MOH) is a frequent, disabling disorder. Despite a controversial pathophysiology convincing evidence attributes a pivotal role to central sensitization. Most patients with MOH initi...

    Authors: Gianluca Coppola, Antonio Currà, Cherubino Di Lorenzo, Vincenzo Parisi, Manuela Gorini, Simona Liliana Sava, Jean Schoenen and Francesco Pierelli

    Citation: BMC Neurology 2010 10:126

    Content type: Research article

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  17. Though vascular factors may be important in the aetiology of late-life depression, it is not clear whether they have a major effect on the risk of depression after a stroke. We investigated the relationship be...

    Authors: Kausik Chatterjee, Susan Fall and David Barer

    Citation: BMC Neurology 2010 10:125

    Content type: Research article

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  18. Parkinson's disease (PD) patients have an increased risk of under-nutrition, but we are unaware of any population based prevalence studies of under-nutrition in PD. The main objective of this study was to iden...

    Authors: Ahmed F Jaafar, William K Gray, Bob Porter, Elizabeth J Turnbull and Richard W Walker

    Citation: BMC Neurology 2010 10:124

    Content type: Research article

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  19. In patients with patent foramen ovale (PFO) there is evidence supporting the hypothesis of a change in right-to-left shunt (RLS) over time. Proven, this could have implications for the care of patients with PF...

    Authors: Christian Tanislav, Manfred Kaps, Marek Jauss, Erwin Stolz, Wolfgang Pabst, Max Nedelmann, Mathias Grebe, Frank Reichenberger and Jens Allendoerfer

    Citation: BMC Neurology 2010 10:123

    Content type: Research article

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  20. Despite lack of outward signs, most individuals after non-disabling stroke (NDS) and transient ischemic attack (TIA) have significant cardiovascular and cerebrovascular disease and are at high risk of a major ...

    Authors: Marilyn MacKay-Lyons, Gordon Gubitz, Nicholas Giacomantonio, Howard Wightman, David Marsters, Kara Thompson, Chris Blanchard, Gail Eskes and Marianne Thornton

    Citation: BMC Neurology 2010 10:122

    Content type: Study protocol

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  21. Synesthesia is, as visual migraine aura, a common and fascinating perceptual phenomenon. Here we present a unique case with synesthesias exclusively during visual migraine auras.

    Authors: Karl B Alstadhaug and Espen Benjaminsen

    Citation: BMC Neurology 2010 10:121

    Content type: Case report

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  22. Syndrome of transient Headache and Neurological Deficits with cerebrospinal fluid Lymphocitosis (HaNDL) is a rare disease which can present with focal neurological deficits and mimic stroke. A neurologist-on-d...

    Authors: Tomas Segura, Francisco Hernandez-Fernandez, Pedro Sanchez-Ayaso, Elena Lozano and Lorenzo Abad

    Citation: BMC Neurology 2010 10:120

    Content type: Case report

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  23. Migraine has been associated with cardiovascular disorders. Endothelial dysfunction may be a mechanism underlying this association. The present study tested the hypothesis that endothelium-dependent vasodilati...

    Authors: Floris H Vanmolkot and Jan N de Hoon

    Citation: BMC Neurology 2010 10:119

    Content type: Research article

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  24. We report on the case of an established perinuclear antineutrophil cytoplasmic antibody (pANCA) associated renal vasculitis being treated with prednisolone and rituximab, where the patient presented with leg w...

    Authors: Alexander J Hamilton, Duncan J Whitehead, Matthew D Bull and Richard J D'Souza

    Citation: BMC Neurology 2010 10:118

    Content type: Case report

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  25. Lyme Neuroborreliosis (LNB) in a human immunodeficiency virus (HIV) positive patient is a rare co-infection and has only been reported four times in literature. No case of an HIV patient with a meningoencephal...

    Authors: Nathalie D van Burgel, Mayke Oosterloo, Frank P Kroon and Alje P van Dam

    Citation: BMC Neurology 2010 10:117

    Content type: Case report

    Published on:

  26. Patients frequently fail to receive adequate pain relief from, or are intolerant of, first-line therapies prescribed for neuropathic pain (NeP). This refractory chronic pain causes psychological distress and i...

    Authors: Melanie Plested, Sangeeta Budhia and Zahava Gabriel

    Citation: BMC Neurology 2010 10:116

    Content type: Research article

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  27. There is a strong maternal parent-of-origin effect in determining susceptibility to multiple sclerosis (MS). One hypothesis is that an abnormal intrauterine milieu leading to impaired fetal development could p...

    Authors: Sreeram V Ramagopalan, Colleen Guimond, Maria Criscuoli, David A Dyment, Sarah-Michelle Orton, Irene M Yee, George C Ebers and Dessa Sadovnick

    Citation: BMC Neurology 2010 10:115

    Content type: Research article

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  28. The Blood Brain Barrier (BBB) maintains the homeostasis of central nervous system by preventing the free passage of macromolecules from the systemic circulation into the brain. This normal physiological functi...

    Authors: Shahrzad Jalali, Yuexi Huang, Daniel J Dumont and Kullervo Hynynen

    Citation: BMC Neurology 2010 10:114

    Content type: Research article

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  29. The role of different chemokine receptors in the pathogenesis of multiple sclerosis (MS) has been extensively investigated; however, little is known about the difference in the role of chemokine receptors betw...

    Authors: Akiyuki Uzawa, Masahiro Mori, Sei Hayakawa, Saeko Masuda, Fumio Nomura and Satoshi Kuwabara

    Citation: BMC Neurology 2010 10:113

    Content type: Research article

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  30. Moyamoya disease (MMD) is an uncommon cerebrovascular condition with unknown etiology characterized by slowly progressive stenosis or occlusion of the bilateral internal carotid arteries associated with an abn...

    Authors: Yoshio Araki, Kazuhiro Yoshikawa, Sho Okamoto, Masaki Sumitomo, Mikio Maruwaka and Toshihiko Wakabayashi

    Citation: BMC Neurology 2010 10:112

    Content type: Research article

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  31. Although some epidemiologic studies found inverse associations between alcohol drinking and Parkinson's disease (PD), the majority of studies found no such significant associations. Additionally, there is only...

    Authors: Wakaba Fukushima, Yoshihiro Miyake, Keiko Tanaka, Satoshi Sasaki, Chikako Kiyohara, Yoshio Tsuboi, Tatsuo Yamada, Tomoko Oeda, Takami Miki, Nobutoshi Kawamura, Nobutaka Sakae, Hidenao Fukuyama, Yoshio Hirota and Masaki Nagai

    Citation: BMC Neurology 2010 10:111

    Content type: Research article

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  32. People with Parkinson disease (PD), even in the presence of symptomatic relief from medical, surgical, and rehabilitative interventions, face a persistent worsening of disability. This disability is characteri...

    Authors: Leland E Dibble, James T Cavanaugh, Gammon M Earhart, Terry D Ellis, Matthew P Ford and Kenneth B Foreman

    Citation: BMC Neurology 2010 10:110

    Content type: Study protocol

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  33. Microclip placement during AVM resection is generally accepted to be a safe practice in neurosurgery. Here, we describe an unusual complication involving cranio-spinal clip migration discovered five years afte...

    Authors: Clark C Chen, Pascal O Zinn, Ekkehard M Kasper and Christopher S Ogilvy

    Citation: BMC Neurology 2010 10:109

    Content type: Case report

    Published on:

  34. Simple, non-invasive tests for early detection of degenerative dementia by use of biomarkers are urgently required. However, up to the present, no validated extracerebral diagnostic markers for the early diagn...

    Authors: Felix Bermejo-Pareja, Desiree Antequera, Teo Vargas, Jose A Molina and Eva Carro

    Citation: BMC Neurology 2010 10:108

    Content type: Research article

    Published on:

  35. Extracellular gelsolin (GSN) and GC-globulin/Vitamin D-binding protein (DBP) appear to play an important role in clearing the actin from extracellular fluids and in modulating cellular responses to anionic bio...

    Authors: Alina Kułakowska, Nicholas J Ciccarelli, Qi Wen, Barbara Mroczko, Wiesław Drozdowski, Maciej Szmitkowski, Paul A Janmey and Robert Bucki

    Citation: BMC Neurology 2010 10:107

    Content type: Research article

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  36. A recent development in non-invasive techniques to predict intracranial pressure (ICP) termed venous ophthalmodynamometry (vODM) has made measurements in absolute units possible. However, there has been little...

    Authors: Henry W Querfurth, Philip Lieberman, Steve Arms, Steve Mundell, Michael Bennett and Craig van Horne

    Citation: BMC Neurology 2010 10:106

    Content type: Research article

    Published on:

  37. Temporal, i.e., 24-hour, weekly, and seasonal patterns in the occurrence of acute cardiovascular and cerebrovascular events are well documented; however, little is known about temporal, especially seasonal, va...

    Authors: Fabrizio Salvi, Ilaria Bartolomei, Michael H Smolensky, Angelo Lorusso, Elena Barbarossa, Anna Maria Malagoni, Paolo Zamboni and Roberto Manfredini

    Citation: BMC Neurology 2010 10:105

    Content type: Research article

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  39. Emotional intelligence (EI) is important for personal, social and career success and has been linked to the frontal anterior cingulate, insula and amygdala regions.

    Authors: Michael Hoffmann, Lourdes Benes Cases, Bronwyn Hoffmann and Ren Chen

    Citation: BMC Neurology 2010 10:103

    Content type: Research article

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  40. The majority of research on health outcomes after a traumatic brain injury is focused on male participants. Information examining gender differences in health outcomes post traumatic brain injury is limited. T...

    Authors: Angela Colantonio, Jocelyn E Harris, Graham Ratcliff, Susan Chase and Kristina Ellis

    Citation: BMC Neurology 2010 10:102

    Content type: Research article

    Published on:

  43. Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare neurodegenerative disorder in humans included in the group of Transmissible Spongiform Encephalopathies or prion diseases. The vast majority of sCJD cases ar...

    Authors: Ana B Rodríguez-Martínez, Joseba M Garrido, Juan J Zarranz, Jose M Arteagoitia, Marian M de Pancorbo, Begoña Atarés, Miren J Bilbao, Isidro Ferrer and Ramón A Juste

    Citation: BMC Neurology 2010 10:99

    Content type: Case report

    Published on:

  44. Vertigo and dizziness are symptoms which are reported frequently in clinical practice. We aimed to develop diagnostic indices for four prevalent vertiginous diseases: benign paroxysmal positional vertigo (BPPV...

    Authors: Otmar Bayer, Jan-Christian Warninghoff and Andreas Straube

    Citation: BMC Neurology 2010 10:98

    Content type: Research article

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    The Erratum to this article has been published in BMC Neurology 2011 11:45

  46. Most people with a spinal cord injury rate neuropathic pain as one of the most difficult problems to manage and there are no medical treatments that provide satisfactory pain relief in most people. Furthermore...

    Authors: Matagne Heutink, Marcel WM Post, Peter Luthart, Lilian EMA Pfennings, Catja A Dijkstra and Eline Lindeman

    Citation: BMC Neurology 2010 10:96

    Content type: Study protocol

    Published on:

  47. In the substantia nigra of Parkinson's disease (PD) patients, increased lipid peroxidation, decreased activities of the mitochondrial complex I of the respiratory chain, catalase and glutathione-peroxidase, an...

    Authors: Pilar del Hoyo, Alberto García-Redondo, Fernando de Bustos, José Antonio Molina, Youssef Sayed, Hortensia Alonso-Navarro, Luis Caballero, Joaquín Arenas, José AG Agúndez and Félix Javier Jiménez-Jiménez

    Citation: BMC Neurology 2010 10:95

    Content type: Research article

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  48. Eukaryotic translation initiation factor 2B (eIF2B), a guanine nucleotide exchange factor (GEF) and a key regulator of translation initiation under normal and stress conditions, causes an autosomal recessive l...

    Authors: Laetitia Horzinski, Liraz Kantor, Aurélia Huyghe, Raphael Schiffmann, Orna Elroy-Stein, Odile Boespflug-Tanguy and Anne Fogli

    Citation: BMC Neurology 2010 10:94

    Content type: Research article

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  49. Infection is a major complication of cerebrospinal fluid shunting procedures. The present report assesses the efficacy of such catheters in both shunts and external ventricular drains (EVDs) against infection ...

    Authors: Raquel Gutiérrez-González, Gregorio R Boto, Cristina Fernández-Pérez and Náyade del Prado

    Citation: BMC Neurology 2010 10:93

    Content type: Research article

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  50. Fragile X syndrome (FXS) is a disorder characterized by a variety of disabilities, including cognitive deficits, attention-deficit/hyperactivity disorder, autism, and other socio-emotional problems. It is hypo...

    Authors: Carlo Paribello, Leeping Tao, Anthony Folino, Elizabeth Berry-Kravis, Michael Tranfaglia, Iryna M Ethell and Douglas W Ethell

    Citation: BMC Neurology 2010 10:91

    Content type: Research article

    Published on:

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