Table 1 Demographic features of ischemic stroke patients with high-grade carotid artery stenosis
| eGFR (mL/min/1.73 m2) | ||||
|---|---|---|---|---|
|
< 45 (n = 76) |
45–59 (n = 65) |
≥ 60 (n = 231) | P | |
| Age (years) | 77 (71–82) | 75 (70–81) | 70 (61–79) | < 0.001* |
| Male (%) | 48 (63.2) | 44 (67.7) | 181 (78.4) | 0.018† |
| Risk factors | ||||
| Hypertension (%) | 72 (94.7) | 53 (81.5) | 186 (80.5) | 0.013† |
| Diabetes mellitus (%) | 46 (60.5) | 29 (44.6) | 100 (43.3) | 0.030† |
| Smoking (%) | 45 (59.2) | 40 (61.5) | 161 (69.7) | 0.170 |
| Hyperlipidemia (%) | 43 (56.6) | 43 (66.2) | 143 (61.9) | 0.500 |
| Atrial fibrillation (%) | 18 (24.0) | 11 (16.9) | 35 (15.2) | 0.211 |
| CAD (%) | 26 (34.2) | 15 (23.1) | 34 (14.7) | 0.001† |
| CHF (%) | 20 (26.3) | 8 (12.3) | 13 (5.6) | < 0.001† |
| Valvular heart disease (%) | 4 (5.3) | 3 (4.6) | 2 (0.9) | 0.043† |
| Peripheral vascular disease (%) | 3 (3.9) | 2 (3.1) | 4 (1.7) | 0.513 |
| Gout (%) | 34 (44.7) | 17 (26.2) | 28 (12.1) | < 0.001† |
| Clinical syndromes | ||||
| TACI (%) | 13 (17.1) | 14 (21.5) | 44 (19.0) | 0.800 |
| PACI (%) | 31 (40.8) | 25 (38.5) | 87 (37.7) | 0.889 |
| LACI (%) | 28 (36.8) | 20 (30.8) | 80 (34.8) | 0.743 |
| Laboratory data | ||||
| Hemoglobin (mmol/L) | 7.63 (6.83–8.32) | 8.32 (7.63–9) | 8.63 (7.88–9.37) | < 0.001* |
| WBC (109/ L) | 7.60 (6.20–9.78) | 7.60 (5.95–9.45) | 7.90 (6.30–9.50) | 0.670 |
| Platelet (109/ L) | 204 (167–268) | 193 (160–261) | 208 (175–255) | 0.604 |
| Glycohemoglobin (%) | 6.3 (5.8–7.3) | 6.1 (5.8–7.0) | 6.0 (5.7–6.9) | 0.279 |
| hs-CRP (nmol/L) | 57.1 (27.6–160) | 47.2 (28.6–91.4) | 42.9 (21.0–85.7) | 0.081 |
| Total cholesterol (mmol/L) | 4.60 (3.62–5.48) | 4.81 (4.27–6) | 4.89 (4.29–5.56) | 0.048* |
| Na (mmol/L) | 138 (136–140) | 138 (136–140) | 138 (136–140) | 0.710 |
| K (mmol/L) | 4.1 (3.8–4.6) | 3.9 (3.6–4.2) | 3.9 (3.6–4.1) | < 0.001* |
| Uric acid (mmol/L) | 0.41 (0.36–0.48) | 0.35 (0.29–0.40) | 0.34 (0.28–0.39) | < 0.001* |
| Antithrombotic treatment | ||||
| Aspirin (%) | 41 (53.9) | 47 (72.3) | 159 (68.8) | 0.032† |
| Clopidogrel (%) | 26 (34.2) | 11 (16.9) | 54 (23.4) | 0.048† |
| Anticoagulant (%) | 9 (11.8) | 9 (13.8) | 30 (13.0) | 0.938 |
| None (%) | 3 (3.9) | 2 (3.1) | 2 (0.9) | 0.032† |